31 Temporal relationship among adiposity, gut microbiota, and insulin resistance in a longitudinal human cohort Kui Deng, Menglei Shuai, Zheqing Zhang, Zengliang Jiang, Yuanqing Fu, Luqi Shen, Ju-Sheng Zheng*, Yu-ming Chen* BMC Med. 19 May 2022. doi.org/10.1186/s12916-022-02376-3
30 Proteomic characterization of Omicron SARS-CoV-2 host response Jianfeng Bao#, Rui Sun#, Jingwen Ai#, Liujia Qian#, Fang Liu#, Hongyu Wang#, Lingling Tan, Xue Cai, Yingqiu Shi, Xiao Liang, Weigang Ge, Jing Wu, Chen Chen, Wenhong Zhang*, Jinsong Huang* & Tiannan Guo* Cell Discovery. 18 May 2022. doi.org/10.1038/s41421-022-00418-x
29 Association Between Postterm Pregnancy and Adverse Growth Outcomes in Preschool-Aged Children Jun Tang, Wanglong Gou, Yuanqing Fu, Kelei Li, Xiaofei Guo, Tao Huang, Huijuan Liu*, Duo Li*, Ju-Sheng Zheng* The American Journal of Clinical Nutrition. 11 May 2022. doi.org/10.1093/ajcn/nqac127
28 Association of gut microbiota with glycaemic traits and incident type 2 diabetes, and modulation by habitual diet: a population-based longitudinal cohort study in Chinese adults Huijun Wang#, Wanglong Gou#, Chang Su, Wenwen Du, Jiguo Zhang, Zelei Miao, Congmei Xiao, Zengliang Jiang, Zhihong Wang, Yuanqing Fu, Xiaofang Jia, Yifei Ouyang, Hongru Jiang, Feifei Huang, Li Li, Bing Zhang*, Ju-Sheng Zheng* Diabetologia. 31 March 2022. doi.org/10.1007/s00125-022-05687-5
27 Multi-omics in COVID-19: Seeing the unseen but overlooked in the clinic Tian Lu, Yingrui Wang, Tiannan Guo* Cell Reports Medicine. March 15 2022. doi.org/10.1016/j.xcrm.2022.100580
26 Stratification of follicular thyroid tumours using data-independent acquisition proteomics and a comprehensive thyroid tissue spectral library Yaoting Sun*, Lu Li, Yan Zhou, Weigang Ge, He Wang, Runxin Wu, Wei Liu, Hao Chen, Qi Xiao, Xue Cai, Zhen Dong, Fangfei Zhang, Junhong Xiao, Guangzhi Wang, Yi He, Jinlong Gao, Oi Lian Kon, Narayanan Gopalakrishna Iyer, Haixia Guan, Xiaodong Teng, Yi Zhu*, Yongfu Zhao*, Tiannan Guo* Molecular Oncology. 23 February 2022. doi.org/10.1002/1878-0261.13198
25 Circulating proteome and progression of type 2 diabetes Wanglong Gou, MSc#, Liang Yue, BSc#, Xin-yi Tang, MPH, Yan-yan Wu, MPH, Xue Cai, MSc, Menglei Shuai, BSc, Zelei Miao, MPH, Yuanqing Fu, PhD, Hao Chen, BSc, Zengliang Jiang, PhD, Jiali Wang, MPH, Yunyi Tian, MPH, Congmei Xiao, MSc, Nan Xiang, BSc, Zhen Wu, PhD, Yu-ming Chen, PhD*, Tiannan Guo, PhD*, Ju-Sheng Zheng, PhD* The Journal of Clinical Endocrinology. 20 February 2022. doi.org/10.1210/clinem/dgac098
24 Human Gut Antibiotic Resistome and Progression of Diabetes Menglei Shuai#, Guoqing Zhang#, Fang-fang Zeng#, Yuanqing Fu#, Xinxiu Liang, Ling Yuan, Fengzhe Xu, Wanglong Gou, Zelei Miao, Zengliang Jiang, Jia-ting Wang, Lai-bao Zhuo, Yu-ming Chen*, Feng Ju*, Ju-Sheng Zheng* Advanced Science. 10 February 2022. doi.org/10.1002/advs.202104965
23 sRAGE alleviates SARS-CoV-2-induced pneumonia in hamster Xiuqin Zhang#, Dan Li#, Rui Sun#, Xinli Hu#, Zhiqi Song#, Xiaotian Ni, Hua Zhu, Tiannan Guo*, Chuan Qin*& Rui-Ping Xiao* Sig Transduct Target Ther. 02 February 2022. doi.org/10.1038/s41392-022-00883-6
22 Mapping the human gut mycobiome in middle-aged and elderly adults: multiomics insights and implications for host metabolic health Menglei Shuai#, Yuanqing Fu#, Hai-li Zhong#, Wanglong Gou, Zengliang Jiang, Yuhui Liang, Zelei Miao, Jin-Jian Xu, Tien Huynh, Mark L Wahlqvist*, Yu-ming Chen*, Ju-Sheng Zheng* Gut Published Online First. 11 January 2022. doi: 10.1136/gutjnl-2021-326298
21 Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19 Xiaojie Bi#, Wei Liu#, Xuan Ding#, Shuang Liang#, Yufen Zheng#, Xiaoli Zhu#, Sheng Quan#, Xiao Yi, Nan Xiang, Juping Du, Haiyan Lyu, Die Yu, Chao Zhang, Luang Xu, Weigang Ge, Xinke Zhan, Jiale He, Zi Xiong, Shun Zhang, Yanchang Li, Ping Xu, Guangjun Zhu, Donglian Wang, Hongguo Zhu, Shiyong Chen, Jun Li, Haihong Zhao, Yi Zhu*, Huafen Liu*, Jiaqin Xu*, Bo Shen*, Tiannan Guo* Cell Reports. 27 December 2021. doi.org/10.1016/j.celrep.2021.110271
20 Proteomics profiling of colorectal cancer progression identifies PLOD2 as a potential therapeutic target Yingkuan Shao#, Kailun Xu#, Xi Zheng, Biting Zhou, Xiuli Zhang, Lin Wang, Yaoting Sun, Dan Li, Ting Chen, Jian Wang, Shaojun Yu, Lifeng Sun, Xiaoming Xu, Shaozhi Dai, Huanhuan Gao, Guan Ruan, Wei Liu, Xue Cai, Tiansheng Zhu, Lina Qi, Jiani Chen, Wangxiong Hu, Xingyue Weng, Yi Zhu, Xueping Xiang, Zhiyuan Hu, Jinfan Li, Lirong Chen, Jimin Shao*, Shu Zheng*, Tiannan Guo* Cancer Communications. 04 December 2021. doi.org/10.1002/cac2.12240
19 A prostate cancer tissue specific spectral library for targeted proteomic analysis Rui Sun, Mengge Lyu, Shuang Liang, Weigang Ge, Yingrui Wang, Xuan Ding, Cheng Zhang, Yan Zhou, Shanjun Chen, Lirong Chen, Tiannan Guo* Proteomics. 20 November 2021. doi.org/10.1002/pmic.202100147
18 Potential Use of Serum Proteomics for Monitoring COVID-19 Progression to Complement RT-PCR Detection Ying Zhang#, Xue Cai#, Weigang Ge#, Donglian Wang#, Guangjun Zhu#, Liujia Qian#, Nan Xiang, Liang Yue, Shuang Liang, Fangfei Zhang, Jing Wang, Kai Zhou, Yufen Zheng, Minjie Lin, Tong Sun, Ruyue Lu, Chao Zhang, Luang Xu, Yaoting Sun, Xiaoxu Zhou, Jing Yu, Mengge Lyu, Bo Shen, Hongguo Zhu*, Jiaqin Xu*, Yi Zhu*, and Tiannan Guo* J. Proteome Res. 16 November 2021. doi.org/10.1021/acs.jproteome.1c00525
17 Computational Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage and Applications to 15 Tumors Weigang Ge#, Xiao Liang#, Fangfei Zhang#, Yifan Hu#, Luang Xu, Nan Xiang, Rui Sun, Wei Liu, Zhangzhi Xue, Xiao Yi, Yaoting Sun, Bo Wang, Jiang Zhu, Cong Lu, Xiaolu Zhan, Lirong Chen, Yan Wu, Zhiguo Zheng, Wangang Gong, Qijun Wu, Jiekai Yu, Zhaoming Ye, Xiaodong Teng, Shiang Huang, Shu Zheng, Tong Liu*, Chunhui Yuan*, Tiannan Guo* J. Proteome Res. 8 November 2021. doi.org/10.1021/acs.jproteome.1c00640
16 Novel deep learning radiomics model for preoperative evaluation of hepatocellular carcinoma differentiation based on computed tomography data Yong Ding#, Shijian Ruan#, Yubizhuo Wang#, Jiayuan Shao#, Rui Sun, Wuwei Tian, Nan Xiang, Weigang Ge, Xiuming Zhang, Kunkai Su, Jingwen Xia, Qiang Huang, Weihai Liu, Qinxue Sun, Haibo Dong*, Mylène C. Q. Farias, Tiannan Guo*, Andrey S. Krylov, Wenjie Liang*, Wenbo Xiao, Xueli Bai, Tingbo Liang* Clin. Transl. Med. 06 November 2021. doi.org/10.1002/ctm2.570
15 SnapShot: Clinical proteomics Yi Zhu, Ruedi Aebersold, Matthias Mann, Tiannan Guo Cell. 2 September 2021. doi:10.1016/j.cell.2021.08.015
14 Precision nutrition for gut microbiome and diabetes research: Application of nutritional n-of-1 clinical trials Ju-Sheng Zheng*, José M Ordovás J Diabetes. 2021 Dec;13(12):1059-1061. doi: 10.1111/1753-0407.13220. Epub 2021 Aug 28
13 Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study Yuanqing Fu#, Fengzhe Xu#, Longda Jiang, Zelei Miao, Xinxiu Liang, Jian Yang, Susanna C Larsson, Ju-Sheng Zheng* BMC Med. 2021 Jul 30;19(1):171. doi: 10.1186/s12916-021-02041-1
12 Individual Postprandial Glycemic Responses to Diet in n-of-1 Trials: Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR) Yue Ma#, Yuanqing Fu#, Yunyi Tian#, Wanglong Gou, Zelei Miao, Min Yang, José M Ordovás, and Ju-Sheng Zheng* The Journal of Nutrition, 01 Oct 2021, 151(10):3158-3167. DOI: 10.1093/jn/nxab227
11 High-Throughput Proteomics and AI for Cancer Biomarker Discovery Qi Xiao, Fangfei Zhang, Luang Xu, Liang Yue, Oi Lian Kon, Yi Zhu*,Tiannan Guo* Advanced Drug Delivery Reviews. 25 June,2021,10.1016/j.addr.2021.113844
10 Eleven routine clinical features predict COVID-19 severity uncovered by machine learning of longitudinal measurements Kai Zhou#, Yaoting Sun#, Lu Li#, Zelin Zang#, Jing Wang#, Jun Li#, Junbo Liang#, Fangfei Zhang, Qiushi Zhang, Weigang Ge, Hao Chen, Xindong Sun, Liang Yue, Xiaomai Wu, Bo Shen, Jiaqin Xu, Hongguo Zhu, Shiyong Chen, Hai Yang, Shigao Huang, Minfei Peng, Dongqing Lv, Chao Zhang, Haihong Zhao, Luxiao Hong, Zhehan Zhou, Haixiao Chen, Xuejun Dong, Chunyu Tu, Minghui Li, Yi Zhu*, Baofu Chen*, Stan Z. Li*, Tiannan Guo* Computational and Structural Biotechnology Journal. 2021. 19: 3640-3649. doi: 10.1016/2021.06.22.
09 Proteomic and metabolomic investigation of serum lactate dehydrogenase elevation in COVID-19 patients Haixi Yan#, Xiao Liang#, Juping Du#, Zebao He#, Yu Wang, Mengge Lyu ,Liang Yue, Fangfei Zhang, Zhangzhi Xue, Luang Xu, Guan Ruan, Jun Li, Hongguo Zhu, Jiaqin Xu, Shiyong Chen, Chao Zhang, Dongqing Lv ,Zongmei Lin, Bo Shen, Yi Zhu*, Biyun Qian*, Haixiao Chen*, Tiannan Guo* Proteomics. 13 May 2021. doi.org/10.1002/pmic.202100002
08 Gut microbiota, inflammation, and molecular signatures of host response to infection Wanglong Gou#, Yuanqing Fu#, Liang Yue#, Geng-Dong Chen#, Xue Cai#, Menglei Shuai#, Fengzhe Xu#, Xiao Yi, Hao Chen, Yi Zhu, Mian-Li Xiao, Zengliang Jiang, Zelei Miao, Congmei Xiao, Bo Shen, Xiaomai Wu, Haihong Zhao, Wenhua Ling, Jun Wang*, Yu-Ming Chen*, Tiannan Guo*, Ju-Sheng Zheng* J Genet Genomics. 2021 Sep 20;48(9):792-802. doi:10.1016/j.jgg.2021.04.002. Epub 2021 May 3
07 Immunometabolism the CyTOF way Liujia Qian, Tiannan Guo* Immunity. Preview. 13 April 2021 10.1016/j.immuni.2021.03.019
06 DIA-based Proteomics Identifies IDH2 as a Targetable Regulator of Acquired Drug Resistance in Chronic Myeloid Leukemia Wei Liu#, Yaoting Sun, Weigang Ge, Fangfei Zhang, Lin Gan, Yi Zhu, Tiannan Guo*, Kexin Liu* Mol Cell Preteomics. DOI:https://doi.org/10.1016/j.mcpro.2021.100187
05 Interpretable Machine Learning Framework Reveals Robust Gut Microbiome Features Associated With Type 2 Diabetes Wanglong Gou#, Chu-Wen Ling#, Yan He#, Zengliang Jiang#, Yuanqing Fu, Fengzhe Xu, Zelei Miao, Ting-Yu Sun, Jie-Sheng Lin, Hui-Lian Zhu, Hongwei Zhou*, Yu-Ming Chen*, Ju-Sheng Zheng* Diabetes Care. 2021 Feb;44(2):358-366. doi: 10.2337/dc20-1536. Epub 2020 Dec 7
04 Multi-organ Proteomic Landscape of COVID-19 Autopsies. Xiu Nie#, Liujia Qian#, Rui Sun#, Bo Huang#, Xiaochuan Dong#, Qi Xiao#, Qiushi Zhang#, Tian Lu, Liang Yue, Shuo Chen, Xiang Li, Yaoting Sun, Li Lu, Luang Xu, Li Yan, Ming Yang, Zhangzhi Xue, Shuang Liang, Xuan Ding, Chunhui Yuan, Li Peng, Wei Liu, Xiao Yi, Mengge Lyu, Guixiang Xiao, Xia Xu, Weigang Ge, Jiale He, Jun Fan, Junhua Wu, Meng Luo, Xiaona Chang, Huaxiong Pan, Xue Cai, Junjie Zhou, Jing Yu, Huanhuan Gao, Mingxing Xie, Sihua Wang, Guan Ruan, Hao Chen, Hua Su, Heng Mei, Danju Luo, Dashi Zhao, Fei Xu, Yan Li, Yi Zhu*, Jiahong Xia*, Yu Hu*, Tiannan Guo* Cell. 2021. 184(3): 775-791. doi: 10.1016/j.cell.2021.01.004
03 ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets Tiansheng Zhu, Hao Chen, Xishan Yan, Zhicheng Wu, Xiaoxu Zhou, Qi Xiao, Weigang Ge, Qiushi Zhang, Chao Xu, Luang Xu, Guan Ruan, Zhangzhi Xue, Chunhui Yuan*, Guo-Bo Chen* and Tiannan Guo* Bioinformatics. January 08, 2021 doi.org/10.1093/bioinformatics/btaa1088
02 Interpretable Machine Learning Framework Reveals Robust Gut Microbiome Features Associated With Type 2 Diabetes Wanglong Gou#, Chu-Wen Ling#, Yan He#, Zengliang Jiang#, Yuanqing Fu, Fengzhe Xu, Zelei Miao, Ting-Yu Sun, Jie-Sheng Lin, Hui-Lian Zhu, Hongwei Zhou*, Yu-Ming Chen*, Ju-Sheng Zheng* Diabetes Care. 2021 Feb;44(2):358-366. doi: 10.2337/dc20-1536. Epub 2020 Dec 7
01 Dietary fruit and vegetable intake, gut microbiota, and type 2 diabetes: results from two large human cohort studies Zengliang Jiang#, Ting-yu Sun#, Yan He#, Wanglong Gou, Luo-shi-yuan Zuo, Yuanqing Fu, Zelei Miao, Menglei Shuai, Fengzhe Xu, Congmei Xiao, Yuhui Liang, Jiali Wang, Yisong Xu, Li-peng Jing, Wenhua Ling, Hongwei Zhou*, Yu-ming Chen* & Ju-Sheng Zheng* BMC Med. 2020 Dec 3;18(1):371. doi: 10.1186/s12916-020-01842-0
